Whole Body Hyperthermia Cancer Treatment

An increase in the core body temperature leads to the production of proteins (cytokines), which play an important role in the immune system. Production begins shortly after the application of whole-body hyperthermia and only normalises after 48 hours.

One of these proteins is interferon-gamma. It has immunostimulating and anti-tumor properties.

In addition to interferon-gamma, the production of interleukin-2 increases. It is responsible for the growth and the production of many different immune cells. Interleukin-2 activates, for example, the natural killer cells that can detect and kill tumor cells.

It is mostly used in combination with other therapies in order to improve treatment efficacy and response rates. In oncology, hyperthermia can act as a potent sensitizer, especially for chemotherapy and radiotherapy.

Hyperthermia usually is taken to mean a body temperature that is higher than normal. High body temperatures are often caused by illnesses, such as fever or heat stroke.

But Hyperthermia can also refer to heat treatment – the carefully controlled use of heat for medical purposes. Here, we will focus on how heat is used by Verita Life to treat cancer.
Whole Body Hyperthermia

Why Choose   Whole Body Hyperthermia Immune Treatment?

When cells in the body are exposed to higher than normal temperatures, changes take place inside the cells. These changes can make the cells more likely to be affected by other treatments such as radiation therapy or chemotherapy.

Very high temperatures can kill cancer cells outright in more focused approaches, such is the case with Local Hyperthermia, but they can also injure or kill normal cells and tissues. This is why hyperthermia must be carefully controlled and should be done by doctors who are experienced in using it.

Our Medical Director Dr Adem Günes is a well-known pioneer in the field of Hyperthermia. Verita Life’s patients benefit from his unique protocols. We can help patients get all the tools they need to help obstruct and destroy cancer cells in a controlled and safe environment.

Currently, instruments have been developed that can deliver heat precisely. And hyperthermia is used to treat many kinds of cancer.
How Is Hyperthermia Used to Treat Cancer?
Depending on the extent of the treated area hyperthermia treatment can be for the local, regional or whole body.
Local hyperthermia
Heat applied to treat a small area having a growth like a tumour is called local hypothermia. In this process, radio waves, ultrasound waves, microwaves, and other energy forms are used to heat the affected area. The application of high temperatures damages the cells and is called thermal ablation. Using small temperatures does not cause much damage and is called mild hyperthermia.
High Intensity Focussed Ultrasound
The use of ultrasound waves is highly focused and is called HIFU. Heat application can be in various ways like
  • Aiming heat energy waves from a machine outside the body at a tumour near the body surface.
  • Putting a probe like a thin needle right into the tumour. The energy released from the tip heats the surrounding tissue.
Radiofrequency Ablation
RFA is the most commonly used thermal ablation, which uses high-frequency radio waves. The treatment is done by inserting a probe into the tumour for a short while. It creates a lot of heat, thus destroying the cells around the insertion spot. There can be a scar on the spot even after removing the dead cells. This process is usually done as an outpatient treatment for tumours where surgery is not possible. It is sometimes used as an additional treatment during other processes, like chemotherapy, surgery, inflation therapy, and so on. Usually, RFA is used to treat liver, lungs, and kidney tumours.
Regional Hyperthermia
In this process, an organ, body cavity, or limb is heated. The temperature may not be high enough to outrightly destroy the cancer cells. Usually, it is used as an accompaniment during radiation therapy and chemotherapy. There are different methods deployed in regional hyperthermia.

One of the approaches is isolation perfusion. The blood supply of the affected part is isolated from the rest of the circulation. This blood is pumped into a heating device, and upon getting heated, it is pumped back. Chemotherapy is done at the same time. Usually, this is used to treat melanomas and sarcomas.

In another approach called continuous hyperthermic peritoneal perfusion during surgery, circulation of the heated chemotherapy drugs is done through the peritoneal cavity. It helps treat some kinds of cancer.

One more approach is deep tissue hyperthermia. By placing devices over the organ's surface, heat gets produced by the high-energy waves. These get directed to the affected area during treatment.
Whole Body Hyperthermia
This treatment method is studied to make chemotherapy for a cancer treatment more effective. Warm water immersion, hot blankets, or thermal chambers are used to raise the body temperature. It is normally done under anesthesia or sedation. During this process, the immune cells seem to become more active for a few hours raising the levels of cell-killing compounds in the blood. The studies on this are ongoing to design and help boost the immune system, which can help fight cancer better.
Pros And Cons of Hyperthermia
Just like any process, hyperthermia also has advantages and disadvantages. There can be some side effects, and they are dependent on the technique used and the body part being treated. Sometimes the side effects can be serious, but in many cases, they do not last long.
  • In local hyperthermia, tumours can be eliminated without surgery. Yes, it is most effective when the exact temperature range is used. And it is difficult to measure the temperature inside a tumour. And each body part responds to temperatures differently. It is a tricky process, and it is under study to find out better methods to use this process.
  • With the application of regional and whole body hyperthermia, the other forms of cancer treatment are more effective. Destroying cancer cells becomes easier when this method is used along with other methods. It is essential to have temperature control in place to get optimum help from hyperthermia.
  • Local hyperthermia causes pain at the site of its application. There can be other symptoms like bleeding, infection, blood clot, burns, swelling, and blistering. There can be damage to the surrounding skin, muscles, and nerves.
  • Indeed, the side effects of regional and whole body hyperthermia depend on the temperature and the body part that is treated. The symptoms seen are vomiting, nausea and diarrhea. There can be some serious side effects like problems with some major organs like the heart and blood vessels.
With treatment plans being evolved and making the necessary improvements in them, fewer side effects are observed now.
The Future of Hyperthermia
It is a promising way for cancer treatment improvement. Being an experimental technique presently, it is not offered at all cancer clinics. But it will evolve with time, and hopefully, a better treatment plan will be deduced in the future for use at most places treating cancer of all body parts.

We don't believe in hopeless cases!

With more than 50 year experience in integrative cancer medicine, we have treated many difficult cases, and we believe there is hope.