Dendritic Cell Therapy

Dendritic Cell Therapy is a powerful form of immune therapy used to fight cancer. It uses resources which already exist within the human body, namely, Dendritic Cells. They trigger the immune system to produce cells which fight cancer, and tell those cells how to do it.

What is the Dendritic cell’s function?

To understand Dendritic Cells, we must first understand how the immune system works. The body has both an innate and an adaptive immune system. The innate immune system is the first line of defence. It is none specific and fights any foreign antigen which enters the body. The adaptive immune system is the immune system which has learned how to fight specific antigens.

How Do Dendritic Cell's Perform

Dendritic cells are dominant protective agents in the human body. They are present in mucous membranes, skin, and blood. So, when a pathogen attacks a body or there are cancer cells, the dendritic cells create a defensive system in the body. This dendritic cell property is adopted to make a treatment plan to treat cancer and make cancer vaccines. Through dendritic cell therapy, these cells get trained to recognize and absorb pathogenic agents and then attack such cells. It helps trigger the entire human body immune system. Dendritic cell therapy helps control cancer cells and tissues from growth and spread. Dendritic cell therapy Australia and other countries use this property of the dendritic cells to treat cancers.
Dendritic cells act as the liaison between your different immune systems. They help the body to notice and recognise antigens which it needs to fight. In the case of cancer treatment, they teach your immune system to identify cancer cells, also called tumour antigens. This means that your adaptive immune system recognises cancer cells and can jump in faster to produce more of the cells which fight cancer. Unfortunately, Dendritic Cells are seldom active in adequate numbers.

It is essential to increase the number of dendritic cells in the body. It gets done via dendritic cell vaccine or dendritic cell generation from monocytes.

Dendritic Cell Vaccine

Dendritic vaccines are helpful in this case. They are potent antigen-presenting cells, having a high capacity to induce T-cell immune responses via provoking pro-inflammatory cytokine responses. It thus stimulates cytotoxic t cells. But its effectiveness can get dampened by the immunosuppressive environment created by the tumor cells. It is necessary to expand their number in the peripheral blood and tissues. It gets done in vivo or ex vivo as per the situation demands.

First immature dc has to be infused in vivo to collect antigens. Then the MoDC are harvested from the patients to yield enough cells for clinical application. They are matured and then re-infused in the patients, which can help induce a tumor-specific immune response. Thus,the DC vaccines help activate the immune system. This therapy is used in prostate cancer, melanoma, and other cancer treatments, which help elicit anti-cancer immunity and help control cancer growth and dissemination.

The advantage of DC vaccines for cancer treatment is their safety and potent ability to combine with other immunotherapies in patients and experimental models.

How Is the Dendritic Vaccine Made

The following method is used to make the DCV
  • Extract blood sample along with cancer cells from the patient
  • Grow the immature precursor cells in the lab
  • Grow the dendritic cells and cancer cells together. It helps the dc to recognize the cancer cells.
  • It is continued for about 2 to 3 weeks when the dendritic cells are ready to help create a robust immune system and fight the cancer cells.
  • It is administered to the patient.
You can see positive results within 3 months of getting vaccinated. The entire therapy can take 6 to 9 months to detect the full effect.

Dendritic Cells Generation from Monocytes

Dendritic cells are potent antigen-presenting cells and are found to play a key role in immune system activation. So, when the body has an inadequate number of dendritic cells, it is essential to produce them. Thus, the monocytes are used to generate them. They get generated from whole blood or apheresis products by culturing enriched monocytes. Different methods get used for culturing and enrichment of monocytes. And then, these are used for generating clinical-grade dendritic cells.

What is Dendritic Cell Cancer Treatment?

Dendritic Cell Cancer therapy is a type of immunotherapy which helps to bolster your immune system and natural defences against cancer, by training and creating more dendritic cells.It is one of the methods used in many a dendritic cell therapy clinic world over nowadays.
It is highly advanced and targeted therapy, with a number of steps:

  • Some dendritic cells are extracted from your body
  • These cells are trained to fight the type of tumour which you have
  • More of these trained cells are grown
  • The cells are then re-injected into the body, acting as a dendritic cell-based cancer vaccine
  • The dendritic cells move to the lymph nodes and activate, multiply and increase cancer fighting cells – T-cells and B-cells.

The benefits have been extensively researched and it has been proven a completely viable and safe alternative to conventional treatment. It has become a pillar in alternative cancer treatment, and has been adopted into many successful programmes across the world.

Types Of Cancer Treated Using Dendritic Cell Therapy

It is combined with other cancer treatments to treat several patients suffering from cancers affecting different parts of the body like.
  • Breast
  • Pancreas
  • Uterus
  • Prostate
  • Oesophagus
  • Intestine
  • Colorectum
  • Kidney
  • Skin
  • Liver
  • Brain
  • Bone
  • Internal organs

Efficacy Of the Dendritic Cell Therapy for Cancer

  • 100% strengthening of immunity
  • 60% reduced resistance to cancer therapy
  • 60% successful in destroying cancer cells
  • 70% success in relapse risk.

Benefits Of Dendric Cell Therapy for Cancer

Response to dendritic cell therapy can vary from person to person. The benefits of this therapy can get listed thus.

  • Target cancer cells without harming healthy cells
  • Improves outcomes in various cancer treatments
  • Milder side effects
  • Shrinks tumor size
  • Moves tumor location where it makes it possible to remove it surgically.
  • Common side effects of dendritic cell therapy
  • Eye inflammation, irritated or dry eyes
  • Joint pain and inflammation
  • Bowel inflammation
  • Stomach pain
  • Bloating
  • Skin rash
  • Shortness of breath
  • Thyroid problem
  • Tiredness
  • Excessive thirst

Why Choose  Dendritic Cell Cancer Treatment with Verita Life?

At Verita Life, immune therapy is a big part of our patient care regimen. Along with other planned programmes that combat cancer cells, leaving your natural defenses intact and strengthening them through proven therapies and natural boosters. Many conventional cancer treatments have severe side effects which the body has to stand up to. Dendritic cell cancer treatment ensures that patients spend less time fighting the symptoms of their cancer treatment, and more time fighting cancer itself.

Verita Life equips you with the best tools possible to fight cancer. As Dendritic Cell Cancer Treatment is complex and highly specialised, only a few laboratories are equipped to perform the training and culturing portion of the process. Verita Life collaborates with a laboratory in Germany to assure the very best quality of cells. We also create personalised treatment plans, which adopt a number of our different integrated treatments, to best suit your body. You can learn more about this process and how we work with you to perform it, by booking a free consultation today.

We don't believe in hopeless cases!

With more than 50 year experience in integrative cancer medicine, we have treated many difficult cases, and we believe there is hope.