Virotherapy is an effective cancer treatment that uses an oncotropic and oncolytic virus with the ability to find and destroy malignant cells in the body. Virotherapy is a gentle and safe treatment, it improves survival and quality of life of patients. The world’s first approved cancer virotherapy medicine is Rigvir.

How Rigvir is Used in the Treatment of Cancer

Oncolytic virotherapy with Rigvir is an active immunotherapy in cancer treatment using a virus that finds and destroys malignant cells in the human body. It has been registered for melanoma treatment in Latvia since 2004 where approximately 75% of melanoma patients are treated with this medicine. Also it is included in the Latvian clinical guidelines for skin melanoma treatment. However in clinical practice it has also been used for treatment of several other cancers, for example, gastric and rectal cancers, where 5-year survival was improved. Rigvir has been shown to significantly reduce the mortality in melanoma stage IB-IIC patients.


The Potential of Rigvir in Cancer Treatment

Further studies on the subject seem to suggest that a significant number of melanoma patients would benefit from prolonging the survival with oncolytic virotherapy treatment, what’s more, this can be achieved without serious side effects.

Despite research and progress in melanoma therapy, mortality rates are high and melanoma is one of the common cancers in the Western world. Small Lung Cancer is one of the most aggressive lung cancer subtypes. Even though its response to chemotherapy and radiation is high, recurrence is common and long term survival does not exceed 5%. Using current standard treatments, the survival of patients with present diagnoses is low. The use of Rigvir provides a great treatment alternative to various cancer patients, and also provides them with a chance of having a good quality of life.

The Development of Rigvir

Rigvir was first developed in Riga, the capital of Latvia. It is a cancer-killing ECHO-7 virus, where ECHO stands for “Enteric Cytopathogenic Human Orphan” virus no. 7. It is found in the intestines, especially of children. “Human Orphan” means that the virus in question is not associated with any known disease.

Rigvir is a live ECHO-7 viruses that have both immune-modulating and cancer cell-killing properties. It has not been genetically modified. In Latvia, it is approved for use in melanoma and against “secondary immunodeficiency,” such as may occur following chemotherapy. Medically, it is prepared for intramuscular injections and must be stored and transported in a frozen state (20º C = -4.0 F).

RigVir is not known to cause any human disease.

Rigvir is not genetically engineered. For some people living with cancer, it could be an important factor when used with standard treatment options in controlling the cancer in their body.

To learn more about Rigvir or other alternative cancer treatments, please contact us and we will get back to you as soon as possible.

Source: Bio Portfolio