Hodgkin’s lymphoma (HL) is a type of cancer that originates in lymphocytes, a type white blood cells that is a part of the lymphatic system. The lymphatic system is part of the immune system. The lymphatic system is responsible for helping the body to fight against infections and diseases and for controlling the flow of lymph (clear fluid that carries immune cells) in the body.
Abnormal growth of cells in the lymph nodes can develop into tumours, commonly in areas such as neck, chest and breastbone, and can spread to other areas of the body. The two main types of lymphocytes in the lymphatic system are B lymphocytes (B cells) and T lymphocytes (T cells). Hodgkin lymphoma frequently originates in B lymphocytes.
There are two main types of Hodgkin lymphoma: Classic Hodgkin’s lymphoma and Nodular lymphocyte-predominant Hodgkin lymphoma. Classic Hodgkin’s lymphoma is the more common of the two. Hodgkin’s lymphoma can develop in both children and adults, but it is more common in people who are in their 20s and mid-50s. There is an 87% five-year survival rate for Hodgkin’s lymphoma.